Day 1 :
Keynote Forum
Iman A Hakim
The University of Arizona Health Sciences, USA
Keynote: Potential role of d-limonene in breast cancer prevention
Time : 10:30-11:10
Biography:
Iman A Hakim is a Professor of Public Health and the Dean of the University of Arizona, College of Public Health. She is internationally known for her translational research on the role of bioactive food compounds in modulation of oxidative damage and prevention of chronic diseases. She has been the Principal Investigator of several large-scale clinical trials focused on nutrition and cancer prevention. She has earned her Medical degree from Cairo University in Egypt and her PhD from Ain-Shams University in Cairo, Egypt. She has received her MPH degree in Preventive Medicine from the University of Arizona, College of Medicine.
Abstract:
Limonene is a bioactive food component found in high concentration in citrus peel oil. It has shown chemopreventive and chemotherapeutic activities in preclinical studies of mammary carcinogenesis. As a fat-soluble compound, d-limonene is more likely to deposit in fatty tissues such as the breast. In our previous work, we have found that lemonade prepared with the whole lemon (Mediterranean-style lemonade) contains high levels of d-limonene. To assess the bioavailability and disposition of d-limonene in humans, we conducted a pilot feeding study with d-limonene-rich lemonade. Healthy adults consumed 40oz of freshly prepared lemonade containing 500 to 600 mg d-limonene daily for 4 weeks. On the first and last consumption days, blood and buttock fat biopsy were collected. Matched plasma and fat biopsies were analyzed for d-limonene levels using gas chromatography and mass spectrometry. Our data showed that d-limonene and its major metabolite are bioavailable after oral consumption of a citrus preparation rich in d-limonene content. There was a significant increase in plasma and adipose d-limonene levels at the end of four weeks. However, adipose d-limonene levels were significantly higher than plasma levels (P=0.009). Our results confirmed the accumulation of d-limonene in adipose tissue after oral dosing in humans and support additional studies of d-limonene for chemoprevention in tissues such as the breast that are comprised of a significant fat fraction.
Keynote Forum
David O Kennedy
David O Kennedy, Northumbria University, UK
Keynote: Modulation of cerebral blood flow, brain metabolism and cognitive function by nutritional interventions
Time : 11:30-12:10
Biography:
David O Kennedy is a Professor of Biological Psychology and the Director of the Brain Performance and Nutrition Research Centre at Northumbria University in the United Kingdom. His research involves investigating the effects of nutritional interventions, including vitamins and minerals, omega-3 fatty acids, amino acids and a host of plant derived extracts and compounds, including polyphenols and caffeine on human brain function. His recently published book, Plants and the Human Brain (Oxford University Press), describes the psychopharmacology and plant ecological ‘secondary metabolite’ roles of a multitude of plant derived compounds
Abstract:
Research has demonstrated that acute or short term administration of a number of nutritional interventions, including a range of food supplements that can beneficially modulate cognitive function or mood. However, the longer term benefits of the optimized nutritional status are less clear. Recent research from our own laboratory has demonstrated that supplementation with both multi vitamins and polyphenols can modulate several physiological parameters in adult humans that should be relevant to healthy brain aging, including cerebral blood flow and brain metabolic parameters. The relevance of these findings to the preservation of cognitive function will be discussed.
Keynote Forum
Fayaz Ahmed Sahibzada
University of Wollongong, Australia
Keynote: Obesity/overweight status and associated factors among Saudi female population
Time : 12:10-12:50
Biography:
Fayaz Ahmed Sahibzada has completed his Master of Science degree in Human Nutrition in 1999 from NWFP Agricultural University, Pakistan. He has worked as a Clinical Dietitian in Abbas Institute of Medical Sciences since 2004. In June 2004, he migrated to Australia as a skilled professional and got Australian Citizenship and completed his MSc in Clinical Nutrition from University of Wollongong, Australia in 2007
Abstract:
During the last few decades, the Kingdom of Saudi Arabia (KSA) experienced rapid socio-cultural changes caused by the accelerating economy in the Arabian Gulf region. That was associated with major changes in the food choices and eating habits which, progressively, became more and more "Westernized". Such a nutritional transition has been claimed for the rising rates of overweight and obesity which were recently observed among Saudi population. Therefore, the objectives of the current study were to determine the overweight and obesity status in a sample of females Saudi adults and to determine the relationship between the obesity and factors associated. A total of 1500 female participants of age ≥19 from Makkah governorate were included the study. A self-reported questionnaire was conducted to collect the data. It composed of socio-economic data, disease history, food habits and anthropometric measurements. Overweight and obesity were defined according to internationally standardized criteria for classification of BMI. Data were analyzed using Statistical Package for Social Sciences (SPSS) software, version 16.0. The data indicated that 23.9% of Saudi female adults were overweight and 27.7% were obese. The most common eating habits encountered were eating two main meals/day, consumed meals with family, drinking fresh juices, sweets and the meals consist mostly of protein. Statistically significant direct correlations were found among these factors (P<0.005). More than 50% of the Saudi adults females were obese or overweight. Additional monitoring of the obesity status is necessary