Moses S S Chow
Western University of Health Sciences, USA
Title: Enhanced cytotoxic effects of herb-drug combinations for resistant cancermechanisms and new therapeutic potentials
Biography
Biography: Moses S S Chow
Abstract
Although more than 50% of anticancer drugs are originally derived from natural products, the use of herbal products as a systemic chemotherapeutic agent is not an accepted practice in Western countries since these products are not approved by regulatory agencies due to lack of definitive clinical efficacy studies. However, there is increasing evidence that a number of herbal products especially in combination with established anticancer drugs can significantly re-sensitize certain anticancer drugs via different mechanisms. Such activity offers new therapeutic potential of their use in cancer chemotherapy, especially for resistant cancer, which is responsible for the high cancer mortality globally. Various examples of herbal product that can exert different cytotoxic effects leading to enhanced activity when combined with conventional anticancer agents will be presented and the advantage of development of such combination products for therapeutic use will be discussed